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Anion Gap Calculator

Calculate anion and delta gaps.

Calculator

Enter the serum electrolyte values in mEq/L.

Reference Information

The anion gap (AG) represents the concentration of all the unmeasured anions in the plasma.

Anion Gap Reference Ranges

PopulationRange
Nonpregnant Adult10 - 17 mmol/L
First Trimester10 - 20 mmol/L
Second Trimester10 - 18 mmol/L
Third Trimester11 - 18 mmol/L

During pregnancy the Anion gap shows a net increase of 1 to 2 mmol/L from the nonpregnant state.

Causes of a High Anion Gap (MUDPILERSO)

  • Methanol
  • Uremia
  • Diabetic Ketoacidosis (DKA) or starvation ketosis
  • Paraldehyde, Phenformin
  • Isopropyl Alcohol, Isoniazid, Infection
  • Lactic Acidosis
  • Ethylene Glycol, ethyl alcohol
  • Rhabdomyolysis
  • Salicylates
  • Other Causes: Hyperalbuminemia, administered anions